ATP-binding cassette (ABC) transporter complex

Term Information

Accession
GO:0043190
Ontology
cellular component
Synonyms
related: ATP-binding cassette (ABC) transporter activity
narrow: ABC-type efflux permease activity
narrow: ABC-type efflux porter activity
narrow: ABC-type uptake permease activity
narrow: mating pheromone exporter
alt_id: GO:0043191
alt_id: GO:0043192
Definition
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. [source: GOC:jl, GOC:mtg_sensu, PMID:11421269, PMID:15111107]
Comment
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Subset
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External References

toggle InterPro (3)
toggle JCVI_TIGRFAMS (20)
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