T cell receptor complex

Term Information

Accession
GO:0042101
Ontology
cellular component
Synonyms
related: TCR
exact: T lymphocyte receptor complex
exact: T-cell receptor complex
exact: T-lymphocyte receptor complex
Definition
A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. [source: GOC:mah, ISBN:0781735149]
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Subset
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