Term Information

Accession

GO:0019104

Ontology

molecular function

Synonyms

related: endonuclease VIII activity

alt_id: GO:0008578

exact: DNA glycosylase activity

Definition

Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. [source: GOC:elh, PMID:11554296]

Comment

Consider also annotating to the molecular function term 'damaged DNA binding ; GO:0003684'.

Subset

• Unavailable

Community

There have been 0 comments for this term. If you would like to view or participate in the community annotation, please continue to the GONUTS page.

Back to top

Term Lineage

Switch to viewing term parents, siblings and children

Back to top

External References

EC (1)

• 3.2.2.-

HAMAP (1)

• MF_00527

InterPro (1)

• IPR005760

JCVI_TIGRFAMS (1)

• TIGR00567

Reactome (1)

• 7370

Back to top