Term Information

Accession

GO:0016469

Ontology

cellular component

Synonyms

related: vacuolar hydrogen-transporting ATPase

exact: hydrogen-transporting two-sector ATPase complex

Definition

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. [source: GOC:mah, ISBN:0716743663, PMID:16691483]

Comment

None

Subset

• goslim_pir
• Unavailable

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Term Lineage

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External References

InterPro (2)

• IPR004100
• IPR018118

JCVI_TIGRFAMS (2)

• TIGR01041
• TIGR01043

Pfam (1)

• PF02874

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