AmiGO: type II protein secretion system complex Details

Term Information

Accession

GO:0015627

Ontology

cellular component

Synonyms

related: general secretion pathway-associated complex

related: Sec-dependent secretion system-associated complex

exact: main terminal branch

exact: MTB

exact: T2SS-associated complexes

Definition

A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex. [source: PMID:16448494]

Comment

Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.

Subset