integrin complex

Term information
Term lineage
External references
109 gene product associations

Term Information

Accession

GO:0008305

Ontology

cellular component

Synonyms

related: laminin receptor protein

Definition

A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands. [source: PMID:17543136]

Comment

None

Subset

Unavailable

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Term Lineage

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all : all [269974 gene products]
- GO:0005575 : cellular_component [206089 gene products]
- - GO:0005623 : cell [143382 gene products]
  - - GO:0044464 : cell part [143363 gene products]
    - - GO:0016020 : membrane [52459 gene products]
      - GO:0044425 : membrane part [33918 gene products]
        
        GO:0031224 : intrinsic to membrane [29683 gene products]
        
        GO:0016021 : integral to membrane [28770 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0044459 : plasma membrane part [4812 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0005886 : plasma membrane [10904 gene products]
        
        GO:0044459 : plasma membrane part [4812 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
      - GO:0044425 : membrane part [33918 gene products]
      - GO:0031224 : intrinsic to membrane [29683 gene products]
        
        GO:0016021 : integral to membrane [28770 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0044459 : plasma membrane part [4812 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
  - GO:0044464 : cell part [143363 gene products]
  - - GO:0016020 : membrane [52459 gene products]
    - - GO:0044425 : membrane part [33918 gene products]
      - GO:0031224 : intrinsic to membrane [29683 gene products]
        
        GO:0016021 : integral to membrane [28770 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0044459 : plasma membrane part [4812 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
      - GO:0005886 : plasma membrane [10904 gene products]
      - GO:0044459 : plasma membrane part [4812 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
    - GO:0044425 : membrane part [33918 gene products]
    - - GO:0031224 : intrinsic to membrane [29683 gene products]
      - GO:0016021 : integral to membrane [28770 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
      - GO:0044459 : plasma membrane part [4812 gene products]
      - GO:0008305 : integrin complex [109 gene products]
        
        GO:0031226 : intrinsic to plasma membrane [2005 gene products]
        
        GO:0005887 : integral to plasma membrane [1831 gene products]
        
        GO:0008305 : integrin complex [109 gene products]
  - GO:0032991 : macromolecular complex [20319 gene products]
  - - GO:0043234 : protein complex [14521 gene products]
    - - GO:0043235 : receptor complex [298 gene products]
      - GO:0008305 : integrin complex [109 gene products]

External References

InterPro (14)

Pfam (3)

PIRSF (2)

PRINTS (2)

PROSITE (1)

PS00243

SMART (1)

SM00187