serine-type peptidase activity

Term information
Term lineage
External references
2179 gene product associations

Term Information

Accession

GO:0008236

Ontology

molecular function

Synonyms

exact: serine protease activity

Definition

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). [source: ISBN:0716720094, http://merops.sanger.ac.uk/about/about_9.htm#CATTYPE]

Comment

None

Subset

Unavailable

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Term Lineage

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all : all [353918 gene products]
- GO:0003674 : molecular_function [267895 gene products]
- - GO:0003824 : catalytic activity [91610 gene products]
  - - GO:0016787 : hydrolase activity [33490 gene products]
    - - GO:0008233 : peptidase activity [7315 gene products]
      - GO:0070011 : peptidase activity, acting on L-amino acid peptides [6714 gene products]
        
        GO:0008236 : serine-type peptidase activity [2179 gene products]
      - GO:0017171 : serine hydrolase activity [2195 gene products]
      - GO:0008236 : serine-type peptidase activity [2179 gene products]

External References

InterPro (15)

JCVI_TIGRFAMS (2)

Pfam (7)

PIRSF (1)

PIRSF036421

PRINTS (2)

PROSITE (5)

SMART (1)

SM00245

SP_KW (1)

KW-0720