prostaglandin-I synthase activity

Term Information

Accession
GO:0008116
Ontology
molecular function
Synonyms
narrow: cytochrome P450 CYP8A1
exact: (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity
exact: PGI(2) synthase activity
exact: PGI(2) synthetase activity
exact: PGI2 synthase activity
exact: PGI2 synthetase activity
exact: prostacyclin synthase activity
exact: prostacycline synthetase activity
exact: prostagladin I2 synthetase activity
Definition
Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate. [source: EC:5.3.99.4]
Comment
None
Subset
None
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External References

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