chemokine activity

Term information
Term lineage
External references
124 gene product associations

Term Information

Accession: GO:0008009
Ontology: molecular function
Synonyms: None
Definition: The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. [source: http://www.copewithcytokines.de/cope.cgi?key=Cytokines]
Comment: See also the molecular function term 'cytokine activity ; GO:0005125'.
Subset: None
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Term Lineage

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all : all [269974 gene products]
- GO:0003674 : molecular_function [183428 gene products]
- - GO:0005488 : binding [78550 gene products]
  - - GO:0005515 : protein binding [29158 gene products]
    - - GO:0005102 : receptor binding [2444 gene products]
      - GO:0005125 : cytokine activity [385 gene products]
        
        GO:0008009 : chemokine activity [124 gene products]
        
        GO:0005126 : cytokine receptor binding [483 gene products]
        
        GO:0042379 : chemokine receptor binding [133 gene products]
        
        GO:0008009 : chemokine activity [124 gene products]
        
        GO:0001664 : G-protein-coupled receptor binding [310 gene products]
        
        GO:0042379 : chemokine receptor binding [133 gene products]
        
        GO:0008009 : chemokine activity [124 gene products]

External References

InterPro (5)

MIPS_funcat (1)

40.02.03.03

Pfam (1)

PF00048

PRINTS (3)

PROSITE (1)

PS00472

SMART (1)

SM00199