neurotransmitter secretion

Term information
Term lineage
External references
47 gene product associations

Term Information

Accession: GO:0007269
Ontology: biological process
Synonyms: exact: neurotransmitter release
Definition: The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. [source: GOC:dph, http://cancerweb.ncl.ac.uk]
Comment: None
Subset: None
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all : all [18608 gene products]
- GO:0008150 : biological_process [15006 gene products]
- - GO:0065007 : biological regulation [7836 gene products]
  - - GO:0065008 : regulation of biological quality [1580 gene products]
    - - GO:0001505 : regulation of neurotransmitter levels [82 gene products]
      - GO:0007269 : neurotransmitter secretion [47 gene products]
  - GO:0009987 : cellular process [12538 gene products]
  - - GO:0007154 : cell communication [4149 gene products]
    - - GO:0007267 : cell-cell signaling [687 gene products]
      - GO:0003001 : generation of a signal involved in cell-cell signaling [156 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
        
        GO:0007268 : synaptic transmission [349 gene products]
        
        GO:0001505 : regulation of neurotransmitter levels [82 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
      - GO:0019226 : transmission of nerve impulse [406 gene products]
      - GO:0007268 : synaptic transmission [349 gene products]
        
        GO:0001505 : regulation of neurotransmitter levels [82 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
    - GO:0051641 : cellular localization [1126 gene products]
    - - GO:0051649 : establishment of localization in cell [1054 gene products]
      - GO:0032940 : secretion by cell [352 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
    - GO:0003001 : generation of a signal involved in cell-cell signaling [156 gene products]
    - - GO:0007269 : neurotransmitter secretion [47 gene products]
    - GO:0032940 : secretion by cell [352 gene products]
    - - GO:0007269 : neurotransmitter secretion [47 gene products]
  - GO:0051234 : establishment of localization [2907 gene products]
  - - GO:0051649 : establishment of localization in cell [1054 gene products]
    - - GO:0032940 : secretion by cell [352 gene products]
      - GO:0007269 : neurotransmitter secretion [47 gene products]
    - GO:0006810 : transport [2880 gene products]
    - - GO:0006836 : neurotransmitter transport [96 gene products]
      - GO:0007269 : neurotransmitter secretion [47 gene products]
      - GO:0046903 : secretion [434 gene products]
      - GO:0032940 : secretion by cell [352 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
  - GO:0051179 : localization [3316 gene products]
  - - GO:0051641 : cellular localization [1126 gene products]
    - - GO:0051649 : establishment of localization in cell [1054 gene products]
      - GO:0032940 : secretion by cell [352 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
    - GO:0051234 : establishment of localization [2907 gene products]
    - - GO:0051649 : establishment of localization in cell [1054 gene products]
      - GO:0032940 : secretion by cell [352 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
      - GO:0006810 : transport [2880 gene products]
      - GO:0006836 : neurotransmitter transport [96 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
        
        GO:0046903 : secretion [434 gene products]
        
        GO:0032940 : secretion by cell [352 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]
  - GO:0032501 : multicellular organismal process [4467 gene products]
  - - GO:0003008 : system process [1592 gene products]
    - - GO:0050877 : neurological system process [1243 gene products]
      - GO:0019226 : transmission of nerve impulse [406 gene products]
        
        GO:0007268 : synaptic transmission [349 gene products]
        
        GO:0001505 : regulation of neurotransmitter levels [82 gene products]
        
        GO:0007269 : neurotransmitter secretion [47 gene products]

External References

InterPro (2)

Pfam (1)

PF02078

PRINTS (1)

PR01368

Reactome (23)