JNK cascade

Term Information

Accession
GO:0007254
Ontology
biological process
Synonyms
narrow: JNK1 cascade
narrow: JNK2 cascade
narrow: JNK3 cascade
narrow: MAPK10 cascade
narrow: MAPK8 cascade
narrow: MAPK9 cascade
broad: SAPK cascade
broad: stress-activated protein kinase cascade
Definition
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress. [source: GOC:bf, PMID:11790549]
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Subset
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