ER overload response

Term information
Term lineage
External references
37 gene product associations

Term Information

Accession: GO:0006983
Ontology: biological process
Synonyms: exact: endoplasmic reticulum overload response; exact: EOR; exact: ER-overload response
Definition: The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB. [source: PMID:10390516]
Comment: None
Subset: None
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all : all [353918 gene products]
- GO:0008150 : biological_process [252790 gene products]
- - GO:0065007 : biological regulation [63128 gene products]
  - - GO:0050789 : regulation of biological process [59418 gene products]
    - - GO:0050794 : regulation of cellular process [54415 gene products]
      - GO:0007165 : signal transduction [27509 gene products]
        
        GO:0007242 : intracellular signaling cascade [8976 gene products]
        
        GO:0006984 : ER-nuclear signaling pathway [301 gene products]
        
        GO:0006983 : ER overload response [37 gene products]
  - GO:0009987 : cellular process [140284 gene products]
  - - GO:0007154 : cell communication [30257 gene products]
    - - GO:0007165 : signal transduction [27509 gene products]
      - GO:0007242 : intracellular signaling cascade [8976 gene products]
        
        GO:0006984 : ER-nuclear signaling pathway [301 gene products]
        
        GO:0006983 : ER overload response [37 gene products]
    - GO:0051716 : cellular response to stimulus [7985 gene products]
    - - GO:0071216 : cellular response to biotic stimulus [210 gene products]
      - GO:0006983 : ER overload response [37 gene products]
      - GO:0033554 : cellular response to stress [5989 gene products]
      - GO:0034976 : response to endoplasmic reticulum stress [226 gene products]
        
        GO:0006983 : ER overload response [37 gene products]
    - GO:0050794 : regulation of cellular process [54415 gene products]
    - - GO:0007165 : signal transduction [27509 gene products]
      - GO:0007242 : intracellular signaling cascade [8976 gene products]
        
        GO:0006984 : ER-nuclear signaling pathway [301 gene products]
        
        GO:0006983 : ER overload response [37 gene products]
  - GO:0050789 : regulation of biological process [59418 gene products]
  - - GO:0050794 : regulation of cellular process [54415 gene products]
    - - GO:0007165 : signal transduction [27509 gene products]
      - GO:0007242 : intracellular signaling cascade [8976 gene products]
        
        GO:0006984 : ER-nuclear signaling pathway [301 gene products]
        
        GO:0006983 : ER overload response [37 gene products]
  - GO:0050896 : response to stimulus [29442 gene products]
  - - GO:0051716 : cellular response to stimulus [7985 gene products]
    - - GO:0071216 : cellular response to biotic stimulus [210 gene products]
      - GO:0006983 : ER overload response [37 gene products]
      - GO:0033554 : cellular response to stress [5989 gene products]
      - GO:0034976 : response to endoplasmic reticulum stress [226 gene products]
        
        GO:0006983 : ER overload response [37 gene products]
    - GO:0009607 : response to biotic stimulus [3421 gene products]
    - - GO:0071216 : cellular response to biotic stimulus [210 gene products]
      - GO:0006983 : ER overload response [37 gene products]
    - GO:0006950 : response to stress [15524 gene products]
    - - GO:0033554 : cellular response to stress [5989 gene products]
      - GO:0034976 : response to endoplasmic reticulum stress [226 gene products]
        
        GO:0006983 : ER overload response [37 gene products]

External References

None.