DNA repair

Term information
Term lineage
External references
4459 gene product associations

Term Information

Accession

GO:0006281

Ontology

biological process

Synonyms

None

Definition

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. [source: PMID:11563486]

Comment

None

Subset