Term Information

Accession

GO:0006273

Ontology

biological process

Synonyms

None

Definition

The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. [source: ISBN:071673706X, ISBN:0815316194]

Comment

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Subset

• Unavailable

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External References

None.