tight junction

Term information
Term lineage
External references
350 gene product associations

Term Information

Accession: GO:0005923
Ontology: cellular component
Synonyms: exact: zonula occludens
Definition: An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. [source: GOC:mah, ISBN:0815332181]
Comment: None
Subset: None
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all : all [353918 gene products]
- GO:0005575 : cellular_component [250721 gene products]
- - GO:0005623 : cell [183680 gene products]
  - - GO:0044464 : cell part [183660 gene products]
    - - GO:0016020 : membrane [70611 gene products]
      - GO:0044425 : membrane part [47071 gene products]
        
        GO:0044459 : plasma membrane part [8963 gene products]
        
        GO:0016327 : apicolateral plasma membrane [489 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0030054 : cell junction [2235 gene products]
        
        GO:0005911 : cell-cell junction [922 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0070160 : occluding junction [374 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0005886 : plasma membrane [18032 gene products]
        
        GO:0044459 : plasma membrane part [8963 gene products]
        
        GO:0016327 : apicolateral plasma membrane [489 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0030054 : cell junction [2235 gene products]
        
        GO:0005911 : cell-cell junction [922 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0070160 : occluding junction [374 gene products]
        
        GO:0005923 : tight junction [350 gene products]
      - GO:0044425 : membrane part [47071 gene products]
      - GO:0044459 : plasma membrane part [8963 gene products]
        
        GO:0016327 : apicolateral plasma membrane [489 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0030054 : cell junction [2235 gene products]
        
        GO:0005911 : cell-cell junction [922 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0070160 : occluding junction [374 gene products]
        
        GO:0005923 : tight junction [350 gene products]
  - GO:0044464 : cell part [183660 gene products]
  - - GO:0016020 : membrane [70611 gene products]
    - - GO:0044425 : membrane part [47071 gene products]
      - GO:0044459 : plasma membrane part [8963 gene products]
        
        GO:0016327 : apicolateral plasma membrane [489 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0030054 : cell junction [2235 gene products]
        
        GO:0005911 : cell-cell junction [922 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0070160 : occluding junction [374 gene products]
        
        GO:0005923 : tight junction [350 gene products]
      - GO:0005886 : plasma membrane [18032 gene products]
      - GO:0044459 : plasma membrane part [8963 gene products]
        
        GO:0016327 : apicolateral plasma membrane [489 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0030054 : cell junction [2235 gene products]
        
        GO:0005911 : cell-cell junction [922 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0070160 : occluding junction [374 gene products]
        
        GO:0005923 : tight junction [350 gene products]
    - GO:0044425 : membrane part [47071 gene products]
    - - GO:0044459 : plasma membrane part [8963 gene products]
      - GO:0016327 : apicolateral plasma membrane [489 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0030054 : cell junction [2235 gene products]
        
        GO:0005911 : cell-cell junction [922 gene products]
        
        GO:0043296 : apical junction complex [474 gene products]
        
        GO:0005923 : tight junction [350 gene products]
        
        GO:0070160 : occluding junction [374 gene products]
        
        GO:0005923 : tight junction [350 gene products]

External References

InterPro (22)

PIRSF (1)

PIRSF005993

PRINTS (21)

PROSITE (1)

PS01346

SP_KW (1)

KW-0796

SP_SL (1)

SL-0265

Wikipedia (1)

Tight_junction