Term Information

Accession

GO:0005884

Ontology

cellular component

Synonyms

exact: microfilament

Definition

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. [source: GOC:mah, ISBN:0198506732, PMID:10666339]

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External References

Wikipedia (1)

• Actin

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