neurofilament

Term Information

Accession
GO:0005883
Ontology
cellular component
Synonyms
exact: type IV intermediate filament
Definition
A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. [source: ISBN:0198506732, ISBN:0716731363, ISBN:0815316194]
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