nucleolus

Term information
Term lineage
External references
1936 gene product associations

Term Information

Accession

GO:0005730

Ontology

cellular component

Synonyms

None

Definition

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [source: ISBN:0198506732]

Comment

None

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all : all [269974 gene products]
- GO:0005575 : cellular_component [206089 gene products]
- - GO:0005623 : cell [143382 gene products]
  - - GO:0044464 : cell part [143363 gene products]
    - - GO:0005622 : intracellular [101767 gene products]
      - GO:0044424 : intracellular part [96440 gene products]
        
        GO:0043229 : intracellular organelle [86188 gene products]
        
        GO:0043231 : intracellular membrane-bounded organelle [79486 gene products]
        
        GO:0005634 : nucleus [24956 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0043232 : intracellular non-membrane-bounded organelle [13128 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
      - GO:0044424 : intracellular part [96440 gene products]
      - GO:0043229 : intracellular organelle [86188 gene products]
        
        GO:0043231 : intracellular membrane-bounded organelle [79486 gene products]
        
        GO:0005634 : nucleus [24956 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0043232 : intracellular non-membrane-bounded organelle [13128 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
  - GO:0044464 : cell part [143363 gene products]
  - - GO:0005622 : intracellular [101767 gene products]
    - - GO:0044424 : intracellular part [96440 gene products]
      - GO:0043229 : intracellular organelle [86188 gene products]
        
        GO:0043231 : intracellular membrane-bounded organelle [79486 gene products]
        
        GO:0005634 : nucleus [24956 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0043232 : intracellular non-membrane-bounded organelle [13128 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
    - GO:0044424 : intracellular part [96440 gene products]
    - - GO:0043229 : intracellular organelle [86188 gene products]
      - GO:0043231 : intracellular membrane-bounded organelle [79486 gene products]
        
        GO:0005634 : nucleus [24956 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0043232 : intracellular non-membrane-bounded organelle [13128 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044446 : intracellular organelle part [22046 gene products]
        
        GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
      - GO:0044446 : intracellular organelle part [22046 gene products]
      - GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
  - GO:0031974 : membrane-enclosed lumen [6407 gene products]
  - - GO:0043233 : organelle lumen [6145 gene products]
    - - GO:0070013 : intracellular organelle lumen [6096 gene products]
      - GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
  - GO:0043226 : organelle [86234 gene products]
  - - GO:0043229 : intracellular organelle [86188 gene products]
    - - GO:0043231 : intracellular membrane-bounded organelle [79486 gene products]
      - GO:0005634 : nucleus [24956 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
      - GO:0043232 : intracellular non-membrane-bounded organelle [13128 gene products]
      - GO:0005730 : nucleolus [1936 gene products]
      - GO:0044446 : intracellular organelle part [22046 gene products]
      - GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
    - GO:0043227 : membrane-bounded organelle [79527 gene products]
    - - GO:0043231 : intracellular membrane-bounded organelle [79486 gene products]
      - GO:0005634 : nucleus [24956 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
    - GO:0043228 : non-membrane-bounded organelle [13128 gene products]
    - - GO:0043232 : intracellular non-membrane-bounded organelle [13128 gene products]
      - GO:0005730 : nucleolus [1936 gene products]
    - GO:0044422 : organelle part [22116 gene products]
    - - GO:0044446 : intracellular organelle part [22046 gene products]
      - GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0044428 : nuclear part [7895 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
      - GO:0043233 : organelle lumen [6145 gene products]
      - GO:0070013 : intracellular organelle lumen [6096 gene products]
        
        GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
  - GO:0044422 : organelle part [22116 gene products]
  - - GO:0044446 : intracellular organelle part [22046 gene products]
    - - GO:0070013 : intracellular organelle lumen [6096 gene products]
      - GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
      - GO:0044428 : nuclear part [7895 gene products]
      - GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]
    - GO:0043233 : organelle lumen [6145 gene products]
    - - GO:0070013 : intracellular organelle lumen [6096 gene products]
      - GO:0031981 : nuclear lumen [4777 gene products]
        
        GO:0005730 : nucleolus [1936 gene products]

External References

InterPro (3)

MIPS_funcat (1)

70.10.07

NIF_Subcellular (1)

sao1820400233

Pfam (2)

PIRSF (1)

PIRSF037708

Rfam (282)

SP_SL (1)

SL-0188

Wikipedia (1)

Nucleolus