DNA replication factor A complex

Term Information

Accession
GO:0005662
Ontology
cellular component
Synonyms
related: single-stranded DNA-binding protein complex
related: SSB
exact: replication protein A
exact: RPA
Definition
A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa. [source: PMID:9242902]
Comment
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Subset
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External References

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