AmiGO: extracellular ligand-gated ion channel activity Details

Term Information

Accession

GO:0005230

Ontology

molecular function

Synonyms

None

Definition

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts. [source: GOC:mtg_transport, ISBN:0815340729]

Comment

None

Subset

Unavailable

Community

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Term Lineage

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all : all [18608 gene products]
- GO:0003674 : molecular_function [15983 gene products]
- - GO:0005215 : transporter activity [1184 gene products]
  - - GO:0022892 : substrate-specific transporter activity [979 gene products]
    - - GO:0022891 : substrate-specific transmembrane transporter activity [836 gene products]
      - GO:0015075 : ion transmembrane transporter activity [726 gene products]
        
        GO:0005216 : ion channel activity [384 gene products]
        
        GO:0015276 : ligand-gated ion channel activity [127 gene products]
        
        GO:0005230 : extracellular ligand-gated ion channel activity [73 gene products]
        
        GO:0022838 : substrate-specific channel activity [394 gene products]
        
        GO:0005216 : ion channel activity [384 gene products]
        
        GO:0015276 : ligand-gated ion channel activity [127 gene products]
        
        GO:0005230 : extracellular ligand-gated ion channel activity [73 gene products]
    - GO:0022857 : transmembrane transporter activity [910 gene products]
    - - GO:0022803 : passive transmembrane transporter activity [409 gene products]
      - GO:0015267 : channel activity [408 gene products]
        
        GO:0022836 : gated channel activity [309 gene products]
        
        GO:0022834 : ligand-gated channel activity [127 gene products]
        
        GO:0015276 : ligand-gated ion channel activity [127 gene products]
        
        GO:0005230 : extracellular ligand-gated ion channel activity [73 gene products]
        
        GO:0022838 : substrate-specific channel activity [394 gene products]
        
        GO:0005216 : ion channel activity [384 gene products]
        
        GO:0015276 : ligand-gated ion channel activity [127 gene products]
        
        GO:0005230 : extracellular ligand-gated ion channel activity [73 gene products]
      - GO:0022891 : substrate-specific transmembrane transporter activity [836 gene products]
      - GO:0015075 : ion transmembrane transporter activity [726 gene products]
        
        GO:0005216 : ion channel activity [384 gene products]
        
        GO:0015276 : ligand-gated ion channel activity [127 gene products]
        
        GO:0005230 : extracellular ligand-gated ion channel activity [73 gene products]
        
        GO:0022838 : substrate-specific channel activity [394 gene products]
        
        GO:0005216 : ion channel activity [384 gene products]
        
        GO:0015276 : ligand-gated ion channel activity [127 gene products]
        
        GO:0005230 : extracellular ligand-gated ion channel activity [73 gene products]

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External References

InterPro (4)

Pfam (1)

PF02931

PRINTS (3)

PROSITE (1)

PS00236

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the Gene Ontology

extracellular ligand-gated ion channel activity

Term Information

Term Lineage

External References