Term Information

Accession

GO:0005085

Ontology

molecular function

Synonyms

narrow: GNRP

alt_id: GO:0008433

alt_id: GO:0019839

exact: GEF

exact: guanyl-nucleotide release factor activity

exact: guanyl-nucleotide releasing factor

Definition

Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. [source: GOC:kd, GOC:mah]

Comment

None

Subset

• Unavailable

Community

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Term Lineage

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External References

InterPro (9)

• IPR000651
• IPR001331
• IPR001895
• IPR005414
• IPR007515
• IPR008937
• IPR010703
• IPR016019
• IPR019804

MIPS_funcat (1)

• 18.02.03

Pfam (5)

• PF00617
• PF00618
• PF04421
• PF06920
• PF07487

PIRSF (1)

• PIRSF034781

PRINTS (1)

• PR01593

PROSITE (4)

• PS00720
• PS00741
• PS50009
• PS50212

Reactome (1)

• 11431

SMART (2)

• SM00147
• SM00229

SP_KW (1)

• KW-0344

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