Term Information

Accession

GO:0004867

Ontology

molecular function

Synonyms

narrow: serpin activity

exact: serine protease inhibitor activity

exact: serine proteinase inhibitor activity

Definition

Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. [source: GOC:ai]

Comment

None

Subset

• Unavailable

Community

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Term Lineage

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External References

HAMAP (2)

• MF_00706
• MF_00778

InterPro (23)

• IPR000215
• IPR000227
• IPR000240
• IPR000295
• IPR000429
• IPR000691
• IPR000737
• IPR000864
• IPR000877
• IPR001239
• IPR002223
• IPR003465
• IPR004094
• IPR006105
• IPR006106
• IPR008086
• IPR010600
• IPR015553
• IPR015555
• IPR015556
• IPR015557
• IPR018112
• IPR020054

Pfam (10)

• PF00014
• PF00079
• PF00228
• PF00280
• PF00299
• PF00713
• PF00720
• PF02428
• PF02822
• PF06668

PIRSF (1)

• PIRSF001640

PRINTS (11)

• PR00290
• PR00292
• PR00293
• PR00294
• PR00654
• PR00676
• PR00759
• PR00777
• PR00780
• PR00808
• PR01706

ProDom (3)

• PD002604
• PD004028
• PD004216

PROSITE (8)

• PS00281
• PS00284
• PS00285
• PS00286
• PS00426
• PS00999
• PS50279
• PS51252

Reactome (1)

• 15233

SMART (4)

• SM00093
• SM00131
• SM00269
• SM00286

SP_KW (1)

• KW-0722

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