Term Information

Accession

GO:0004419

Ontology

molecular function

Synonyms

related: 3-hydroxy-3-methylglutaryl CoA cleaving enzyme

related: hydroxymethylglutaryl coenzyme A-cleaving enzyme

exact: (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)

exact: (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity

exact: 3-hydroxy-3-methylglutarate-CoA lyase activity

exact: 3-hydroxy-3-methylglutaryl coenzyme A lyase activity

exact: 3-hydroxy-3-methylglutaryl-CoA lyase activity

exact: HMG-CoA lyase activity

exact: hydroxymethylglutaryl coenzyme A lyase activity

Definition

Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate. [source: EC:4.1.3.4]

Comment

None

Subset

• Unavailable

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Term Lineage

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External References

EC (1)

• 4.1.3.4

InterPro (1)

• IPR000138

MetaCyc (1)

• HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN

PROSITE (1)

• PS01062

Reactome (1)

• 74178

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