serine-type endopeptidase activity

Term Information

Accession
GO:0004252
Ontology
molecular function
Synonyms
related: blood coagulation factor activity
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). [source: GOC:mah, ISBN:0716720094, http://merops.sanger.ac.uk/about/about_9.htm#CATTYPE]
Comment
None
Subset
  • Unavailable
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External References

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