Term Information

Accession

GO:0004190

Ontology

molecular function

Synonyms

exact: aspartic endopeptidase activity

exact: aspartic protease activity

exact: aspartyl protease activity

exact: carboxyl protease activity

Definition

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. [source: ISBN:0198506732]

Comment

None

Subset

• Unavailable

Community

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Term Lineage

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External References

EC (1)

• 3.4.23

HAMAP (1)

• MF_00161

InterPro (16)

• IPR000045
• IPR000250
• IPR000588
• IPR000696
• IPR001461
• IPR001641
• IPR001872
• IPR001969
• IPR001995
• IPR005081
• IPR007369
• IPR009007
• IPR009119
• IPR009120
• IPR012848
• IPR019103

JCVI_TIGRFAMS (3)

• TIGR00140
• TIGR00142
• TIGR02854

Pfam (9)

• PF00026
• PF01252
• PF01478
• PF01829
• PF03419
• PF03539
• PF04258
• PF07966
• PF09668

PRINTS (8)

• PR00731
• PR00781
• PR00792
• PR00863
• PR00920
• PR00977
• PR01815
• PR01816

ProDom (1)

• PD013079

PROSITE (4)

• MF_00161
• PS00141
• PS00855
• PS50175

Reactome (1)

• 1933

SP_KW (1)

• KW-0064

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