progressive alteration of chromatin during cell aging

Term Information

Accession
GO:0001301
Ontology
biological process
Synonyms
related: age-dependent accumulation of genetic damage
exact: progressive alteration of chromatin during cell ageing
Definition
The process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype. [source: GOC:jh, PMID:12044938]
Comment
None
Subset
None
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External References

None.