second spliceosomal transesterification activity
Term Information
- Accession
- GO:0000386
- Ontology
- molecular function
- Synonyms
- narrow: lariat formation, 5'-splice site cleavage
- broad: 3'-splice site cleavage, exon ligation
- Definition
- Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. [source:
GOC:krc, ISBN:0879695897]
- Comment
- None
- Subset
- None
- Community
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External References
None.
all : all
[269974 gene products]
GO:0003674 : molecular_function
[183428 gene products]
