generation of catalytic spliceosome for second transesterification step

Term information
Term lineage
External references
20 gene product associations

Term Information

Accession: GO:0000350
Ontology: biological process
Synonyms: related: catalytic spliceosome assembly for second transesterification step; related: lariat formation, 5'-splice site cleavage; narrow: formation of catalytic U12-type spliceosome for second transesterification step; narrow: formation of catalytic U2-type spliceosome for second transesterification step; narrow: formation of spliceosomal A2-2 complex; narrow: formation of spliceosomal C1 complex; narrow: spliceosomal A2-3 complex biosynthesis; narrow: spliceosomal A2-3 complex formation; narrow: spliceosomal C2 complex biosynthesis; narrow: spliceosomal C2 complex formation; alt_id: GO:0000358; alt_id: GO:0000359; exact: formation of catalytic spliceosome for second transesterification step
Definition: Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. [source: GOC:krc, ISBN:0879695897]
Comment: Note that this step represents formation of the A2-3 complex (yeast) or the C2 complex (mammalian).
Subset: None
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all : all [269974 gene products]
- GO:0008150 : biological_process [182912 gene products]
- - GO:0044085 : cellular component biogenesis [7219 gene products]
  - - GO:0022607 : cellular component assembly [5119 gene products]
    - - GO:0065003 : macromolecular complex assembly [3649 gene products]
      - GO:0034622 : cellular macromolecular complex assembly [2548 gene products]
        
        GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0022613 : ribonucleoprotein complex biogenesis [2210 gene products]
    - - GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
      - GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
  - GO:0016043 : cellular component organization [15212 gene products]
  - - GO:0022607 : cellular component assembly [5119 gene products]
    - - GO:0065003 : macromolecular complex assembly [3649 gene products]
      - GO:0034622 : cellular macromolecular complex assembly [2548 gene products]
        
        GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0043933 : macromolecular complex subunit organization [4222 gene products]
    - - GO:0034621 : cellular macromolecular complex subunit organization [3127 gene products]
      - GO:0034622 : cellular macromolecular complex assembly [2548 gene products]
        
        GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
      - GO:0065003 : macromolecular complex assembly [3649 gene products]
      - GO:0034622 : cellular macromolecular complex assembly [2548 gene products]
        
        GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
  - GO:0009987 : cellular process [92775 gene products]
  - - GO:0034621 : cellular macromolecular complex subunit organization [3127 gene products]
    - - GO:0034622 : cellular macromolecular complex assembly [2548 gene products]
      - GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0044237 : cellular metabolic process [55797 gene products]
    - - GO:0044260 : cellular macromolecule metabolic process [39721 gene products]
      - GO:0016070 : RNA metabolic process [15626 gene products]
        
        GO:0016071 : mRNA metabolic process [1863 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0006396 : RNA processing [4229 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0008380 : RNA splicing [1167 gene products]
        
        GO:0000375 : RNA splicing, via transesterification reactions [636 gene products]
        
        GO:0000377 : RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [610 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0022613 : ribonucleoprotein complex biogenesis [2210 gene products]
    - - GO:0022618 : ribonucleoprotein complex assembly [498 gene products]
      - GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
  - GO:0008152 : metabolic process [73553 gene products]
  - - GO:0044237 : cellular metabolic process [55797 gene products]
    - - GO:0044260 : cellular macromolecule metabolic process [39721 gene products]
      - GO:0016070 : RNA metabolic process [15626 gene products]
        
        GO:0016071 : mRNA metabolic process [1863 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0006396 : RNA processing [4229 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0008380 : RNA splicing [1167 gene products]
        
        GO:0000375 : RNA splicing, via transesterification reactions [636 gene products]
        
        GO:0000377 : RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [610 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0043170 : macromolecule metabolic process [44809 gene products]
    - - GO:0044260 : cellular macromolecule metabolic process [39721 gene products]
      - GO:0016070 : RNA metabolic process [15626 gene products]
        
        GO:0016071 : mRNA metabolic process [1863 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0006396 : RNA processing [4229 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0008380 : RNA splicing [1167 gene products]
        
        GO:0000375 : RNA splicing, via transesterification reactions [636 gene products]
        
        GO:0000377 : RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [610 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
      - GO:0010467 : gene expression [25040 gene products]
      - GO:0006396 : RNA processing [4229 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0008380 : RNA splicing [1167 gene products]
        
        GO:0000375 : RNA splicing, via transesterification reactions [636 gene products]
        
        GO:0000377 : RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [610 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0006807 : nitrogen compound metabolic process [33690 gene products]
    - - GO:0006139 : nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [28461 gene products]
      - GO:0016070 : RNA metabolic process [15626 gene products]
        
        GO:0016071 : mRNA metabolic process [1863 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0006396 : RNA processing [4229 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0008380 : RNA splicing [1167 gene products]
        
        GO:0000375 : RNA splicing, via transesterification reactions [636 gene products]
        
        GO:0000377 : RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [610 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
    - GO:0044238 : primary metabolic process [61249 gene products]
    - - GO:0006139 : nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [28461 gene products]
      - GO:0016070 : RNA metabolic process [15626 gene products]
        
        GO:0016071 : mRNA metabolic process [1863 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0006396 : RNA processing [4229 gene products]
        
        GO:0006397 : mRNA processing [1448 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]
        
        GO:0008380 : RNA splicing [1167 gene products]
        
        GO:0000375 : RNA splicing, via transesterification reactions [636 gene products]
        
        GO:0000377 : RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [610 gene products]
        
        GO:0000398 : nuclear mRNA splicing, via spliceosome [599 gene products]
        
        GO:0000393 : spliceosomal conformational changes to generate catalytic conformation [43 gene products]
        
        GO:0000350 : generation of catalytic spliceosome for second transesterification step [20 gene products]

External References

None.