protein phosphatase type 2A complex

Term information
Term lineage
External references
89 gene product associations

Term Information

Accession: GO:0000159
Ontology: cellular component
Synonyms: None
Definition: A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. [source: GOC:mah, ISBN:0198547684, PMID:17245430]
Comment: None
Subset: None
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all : all [269974 gene products]
- GO:0005575 : cellular_component [206089 gene products]
- - GO:0005623 : cell [143382 gene products]
  - - GO:0044464 : cell part [143363 gene products]
    - - GO:0005622 : intracellular [101767 gene products]
      - GO:0044424 : intracellular part [96440 gene products]
        
        GO:0000159 : protein phosphatase type 2A complex [89 gene products]
      - GO:0044424 : intracellular part [96440 gene products]
      - GO:0000159 : protein phosphatase type 2A complex [89 gene products]
      - GO:0008287 : protein serine/threonine phosphatase complex [266 gene products]
      - GO:0000159 : protein phosphatase type 2A complex [89 gene products]
  - GO:0044464 : cell part [143363 gene products]
  - - GO:0005622 : intracellular [101767 gene products]
    - - GO:0044424 : intracellular part [96440 gene products]
      - GO:0000159 : protein phosphatase type 2A complex [89 gene products]
    - GO:0044424 : intracellular part [96440 gene products]
    - - GO:0000159 : protein phosphatase type 2A complex [89 gene products]
    - GO:0008287 : protein serine/threonine phosphatase complex [266 gene products]
    - - GO:0000159 : protein phosphatase type 2A complex [89 gene products]
  - GO:0032991 : macromolecular complex [20319 gene products]
  - - GO:0043234 : protein complex [14521 gene products]
    - - GO:0008287 : protein serine/threonine phosphatase complex [266 gene products]
      - GO:0000159 : protein phosphatase type 2A complex [89 gene products]

External References

InterPro (2)

Pfam (1)

PF01603

PIRSF (2)

PRINTS (1)

PR00600