Term Information [More information on activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway]

Accession
GO:0097296
Name
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Ontology
biological_process
Synonyms
activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway, activation of initiator caspase activity
Definition
Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway. Source: GOC:mtg_apoptosis
Comment
Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Note that GO:0097296 should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the apoptotic signaling pathway (also known as an initiator caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.
History
See term history for GO:0097296 at QuickGO
Subset
None
Community
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Ancestors of activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097296)
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activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) biological_process (GO:0008150)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) biological regulation (GO:0065007)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) metabolic process (GO:0008152)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cellular process (GO:0009987)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) organic substance metabolic process (GO:0071704)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) regulation of biological process (GO:0050789)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cellular metabolic process (GO:0044237)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) macromolecule metabolic process (GO:0043170)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) molecular_function (GO:0003674)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of biological process (GO:0048518)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) primary metabolic process (GO:0044238)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of metabolic process (GO:0019222)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) catalytic activity (GO:0003824)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cellular macromolecule metabolic process (GO:0044260)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of metabolic process (GO:0009893)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) protein metabolic process (GO:0019538)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) regulation of cellular process (GO:0050794)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of macromolecule metabolic process (GO:0060255)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of primary metabolic process (GO:0080090)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cellular protein metabolic process (GO:0044267)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) hydrolase activity (GO:0016787)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cellular process (GO:0048522)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of macromolecule metabolic process (GO:0010604)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) proteolysis (GO:0006508)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular metabolic process (GO:0031323)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of molecular function (GO:0065009)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of protein metabolic process (GO:0051246)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) single-organism process (GO:0044699)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) peptidase activity (GO:0008233)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cellular metabolic process (GO:0031325)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of molecular function (GO:0044093)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of protein metabolic process (GO:0051247)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of catalytic activity (GO:0050790)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular protein metabolic process (GO:0032268)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) single-organism cellular process (GO:0044763)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cell death (GO:0008219)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) peptidase activity, acting on L-amino acid peptides (GO:0070011)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of catalytic activity (GO:0043085)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cellular protein metabolic process (GO:0032270)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of hydrolase activity (GO:0051336)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of proteolysis (GO:0030162)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) response to stimulus (GO:0050896)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) signaling (GO:0023052)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cell communication (GO:0007154)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cellular response to stimulus (GO:0051716)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cysteine-type peptidase activity (GO:0008234)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) endopeptidase activity (GO:0004175)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) gene expression (GO:0010467)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of hydrolase activity (GO:0051345)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of proteolysis (GO:0045862)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) programmed cell death (GO:0012501)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cell death (GO:0010941)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of peptidase activity (GO:0052547)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) single organism signaling (GO:0044700)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) apoptotic process (GO:0006915)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cysteine-type endopeptidase activity (GO:0004197)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cell death (GO:0010942)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of peptidase activity (GO:0010952)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) protein maturation (GO:0051604)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cell communication (GO:0010646)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of endopeptidase activity (GO:0052548)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of programmed cell death (GO:0043067)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of response to stimulus (GO:0048583)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of signaling (GO:0023051)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) signal transduction (GO:0007165)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) apoptotic signaling pathway (GO:0097190)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cysteine-type endopeptidase activity involved in apoptotic process (GO:0097153)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cell communication (GO:0010647)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of endopeptidase activity (GO:0010950)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of programmed cell death (GO:0043068)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of response to stimulus (GO:0048584)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of signaling (GO:0023056)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) protein processing (GO:0016485)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of apoptotic process (GO:0042981)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cysteine-type endopeptidase activity (GO:2000116)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of signal transduction (GO:0009966)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) signal transducer activity (GO:0004871)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred positively_regulates relation] positively_regulates (inferred) cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097199)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of apoptotic process (GO:0043065)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cysteine-type endopeptidase activity (GO:2001056)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of signal transduction (GO:0009967)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of apoptotic signaling pathway (GO:2001233)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) zymogen activation (GO:0031638)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [is_a relation] is_a  activation of cysteine-type endopeptidase activity (GO:0097202)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of apoptotic signaling pathway (GO:2001235)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001267)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [is_a relation] is_a  activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [is_a relation] is_a  positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001269)

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