Term Information [More information on cysteine-type endopeptidase activity involved in apoptotic signaling pathway]

Accession
GO:0097199
Name
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Ontology
molecular_function
Synonyms
cysteine-type endopeptidase activity involved in apoptotic signalling pathway, activator caspase activity, apical caspase activity, initiator caspase activity
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. Source: GOC:mtg_apoptosis, PMID:11717445, http://en.wikipedia.org/wiki/Caspase
Comment
Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.
History
See term history for GO:0097199 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0097199 from QuickGO

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Ancestors of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097199)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) proteolysis (GO:0006508)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) biological regulation (GO:0065007)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) peptidase activity (GO:0008233)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cell death (GO:0008219)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) peptidase activity, acting on L-amino acid peptides (GO:0070011)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) regulation of biological process (GO:0050789)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) cysteine-type peptidase activity (GO:0008234)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) endopeptidase activity (GO:0004175)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) programmed cell death (GO:0012501)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) regulation of cellular process (GO:0050794)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) apoptotic process (GO:0006915)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [is_a relation] is_a  cysteine-type endopeptidase activity (GO:0004197)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) signal transduction (GO:0007165)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [part_of relation] part_of  apoptotic signaling pathway (GO:0097190)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [is_a relation] is_a  cysteine-type endopeptidase activity involved in apoptotic process (GO:0097153)
cysteine-type endopeptidase activity involved in apoptotic signaling pathway [is_a relation] is_a  signal transducer activity (GO:0004871)
Children of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097199)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001268) [negatively_regulates relation] negatively_regulates  cysteine-type endopeptidase activity involved in apoptotic signaling pathway
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001269) [positively_regulates relation] positively_regulates  cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001267) [regulates relation] regulates  cysteine-type endopeptidase activity involved in apoptotic signaling pathway
None.