Term Information [More information on extrinsic apoptotic signaling pathway]

Accession
GO:0097191
Name
extrinsic apoptotic signaling pathway
Ontology
biological_process
Synonyms
extrinsic apoptotic pathway, extrinsic apoptotic signalling pathway, death receptor-mediated apoptosis, extrinsic apoptosis, extrinsic apoptotic signaling pathway in presence of ligand
Definition
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. Source: PMID:17340152, GOC:mtg_apoptosis, GOC:yaf
Comment
Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer.
History
See term history for GO:0097191 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0097191 from QuickGO

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Ancestors of extrinsic apoptotic signaling pathway (GO:0097191)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
extrinsic apoptotic signaling pathway [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
extrinsic apoptotic signaling pathway [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
extrinsic apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) death (GO:0016265)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cell death (GO:0008219)
extrinsic apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) programmed cell death (GO:0012501)
extrinsic apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
extrinsic apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) apoptotic process (GO:0006915)
extrinsic apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
extrinsic apoptotic signaling pathway [is_a relation] is_a  apoptotic signaling pathway (GO:0097190)
extrinsic apoptotic signaling pathway [is_a relation] is_a  cell surface receptor signaling pathway (GO:0007166)
Children of extrinsic apoptotic signaling pathway (GO:0097191)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
B cell receptor apoptotic signaling pathway (GO:1990117) [is_a relation] is_a  extrinsic apoptotic signaling pathway
death-inducing signaling complex assembly (GO:0071550) [part_of relation] part_of  extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand (GO:0097192) [is_a relation] is_a  extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625) [is_a relation] is_a  extrinsic apoptotic signaling pathway
fibroblast growth factor receptor apoptotic signaling pathway (GO:1902178) [is_a relation] is_a  extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway (GO:2001237) [negatively_regulates relation] negatively_regulates  extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway (GO:2001238) [positively_regulates relation] positively_regulates  extrinsic apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway (GO:2001236) [regulates relation] regulates  extrinsic apoptotic signaling pathway
ripoptosome assembly involved in extrinsic apoptotic signaling pathway (GO:1901025) [part_of relation] part_of  extrinsic apoptotic signaling pathway
None.