Term Information [More information on 14-3-3 protein binding]

Accession
GO:0071889
Name
14-3-3 protein binding
Ontology
molecular_function
Synonyms
None
Definition
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins. Source: PR:000003237, InterPro:IPR000308, PMID:15167810, GOC:cna, PMID:19575580, GOC:mah
Comment
None
History
See term history for GO:0071889 at QuickGO
Subset
None
Community
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Feedback
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Contacting server...
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Graph of GO:0071889 from QuickGO

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Ancestors of 14-3-3 protein binding (GO:0071889)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
14-3-3 protein binding [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
14-3-3 protein binding [is_a relation] is_a  binding (GO:0005488)
14-3-3 protein binding [is_a relation] is_a  protein binding (GO:0005515)

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None.