Term Information [More information on ubiquitin-dependent protein catabolic process via the N-end rule pathway]

Accession
GO:0071596
Name
ubiquitin-dependent protein catabolic process via the N-end rule pathway
Ontology
biological_process
Synonyms
ubiquitin-dependent protein breakdown via the N-end rule pathway, ubiquitin-dependent protein catabolism via the N-end rule pathway, ubiquitin-dependent protein degradation via the N-end rule pathway
Definition
The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. Source: PMID:19246002, GOC:rb, GOC:mah, PMID:9112437
Comment
None
History
See term history for GO:0071596 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0071596 from QuickGO

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Ancestors of ubiquitin-dependent protein catabolic process via the N-end rule pathway (GO:0071596)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) catabolic process (GO:0009056)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) organic substance catabolic process (GO:1901575)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular catabolic process (GO:0044248)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular macromolecule metabolic process (GO:0044260)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) macromolecule catabolic process (GO:0009057)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular macromolecule catabolic process (GO:0044265)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular protein metabolic process (GO:0044267)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) protein catabolic process (GO:0030163)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred part_of relation] part_of (inferred) cellular protein catabolic process (GO:0044257)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred is_a relation] is_a (inferred) proteolysis (GO:0006508)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred is_a relation] is_a (inferred) modification-dependent macromolecule catabolic process (GO:0043632)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred is_a relation] is_a (inferred) proteolysis involved in cellular protein catabolic process (GO:0051603)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred is_a relation] is_a (inferred) modification-dependent protein catabolic process (GO:0019941)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred is_a relation] is_a (inferred) proteasomal protein catabolic process (GO:0010498)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [Inferred is_a relation] is_a (inferred) ubiquitin-dependent protein catabolic process (GO:0006511)
ubiquitin-dependent protein catabolic process via the N-end rule pathway [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)

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