Term Information [More information on phosphorylation of RNA polymerase II C-terminal domain]

Accession
GO:0070816
Name
phosphorylation of RNA polymerase II C-terminal domain
Ontology
biological_process
Synonyms
alt. id: GO:0016245
CTD domain phosphorylation of RNA polymerase II, generation of II(0) form of RNA polymerase II, generation of hyperphosphorylated CTD of RNA polymerase II, hyperphosphorylation of RNA polymerase II C-terminal domain
Definition
The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex. Source: GOC:krc, PMID:17079683, GOC:mah
Comment
None
History
See term history for GO:0070816 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0070816 from QuickGO

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Ancestors of phosphorylation of RNA polymerase II C-terminal domain (GO:0070816)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) metabolic process (GO:0008152)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular metabolic process (GO:0044237)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) nitrogen compound metabolic process (GO:0006807)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) organic substance metabolic process (GO:0071704)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) biosynthetic process (GO:0009058)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular aromatic compound metabolic process (GO:0006725)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular nitrogen compound metabolic process (GO:0034641)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) heterocycle metabolic process (GO:0046483)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) organic cyclic compound metabolic process (GO:1901360)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) primary metabolic process (GO:0044238)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular biosynthetic process (GO:0044249)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) macromolecule metabolic process (GO:0043170)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) nucleobase-containing compound metabolic process (GO:0006139)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) organic substance biosynthetic process (GO:1901576)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of metabolic process (GO:0019222)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) aromatic compound biosynthetic process (GO:0019438)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular macromolecule metabolic process (GO:0044260)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular nitrogen compound biosynthetic process (GO:0044271)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) heterocycle biosynthetic process (GO:0018130)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) nucleic acid metabolic process (GO:0090304)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) organic cyclic compound biosynthetic process (GO:1901362)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of cellular metabolic process (GO:0031323)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of nitrogen compound metabolic process (GO:0051171)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of primary metabolic process (GO:0080090)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) macromolecule biosynthetic process (GO:0009059)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) nucleobase-containing compound biosynthetic process (GO:0034654)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of biosynthetic process (GO:0009889)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of macromolecule metabolic process (GO:0060255)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of nucleobase-containing compound metabolic process (GO:0019219)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) RNA metabolic process (GO:0016070)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of cellular biosynthetic process (GO:0031326)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of macromolecule biosynthetic process (GO:0010556)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of RNA metabolic process (GO:0051252)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) RNA biosynthetic process (GO:0032774)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) cellular macromolecule biosynthetic process (GO:0034645)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) gene expression (GO:0010467)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) macromolecule modification (GO:0043412)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) nucleic acid-templated transcription (GO:0097659)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) phosphorus metabolic process (GO:0006793)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) protein metabolic process (GO:0019538)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of RNA biosynthetic process (GO:2001141)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) cellular protein metabolic process (GO:0044267)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) phosphate-containing compound metabolic process (GO:0006796)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) protein modification process (GO:0036211)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of cellular macromolecule biosynthetic process (GO:2000112)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of gene expression (GO:0010468)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of nucleic acid-templated transcription (GO:1903506)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) transcription, DNA-templated (GO:0006351)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) cellular protein modification process (GO:0006464)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) phosphorylation (GO:0016310)
phosphorylation of RNA polymerase II C-terminal domain [Inferred is_a relation] is_a (inferred) regulation of transcription, DNA-templated (GO:0006355)
phosphorylation of RNA polymerase II C-terminal domain [Inferred regulates relation] regulates (inferred) transcription from RNA polymerase II promoter (GO:0006366)
phosphorylation of RNA polymerase II C-terminal domain [is_a relation] is_a  protein phosphorylation (GO:0006468)
phosphorylation of RNA polymerase II C-terminal domain [is_a relation] is_a  regulation of transcription from RNA polymerase II promoter (GO:0006357)
Children of phosphorylation of RNA polymerase II C-terminal domain (GO:0070816)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cyclin-dependent protein kinase activating kinase holoenzyme complex (GO:0019907) [capable_of part of relation] capable_of part of  phosphorylation of RNA polymerase II C-terminal domain
negative regulation of phosphorylation of RNA polymerase II C-terminal domain (GO:1901408) [negatively_regulates relation] negatively_regulates  phosphorylation of RNA polymerase II C-terminal domain
phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex (GO:1901921) [is_a relation] is_a  phosphorylation of RNA polymerase II C-terminal domain
phosphorylation of RNA polymerase II C-terminal domain serine 2 residues (GO:0071619) [is_a relation] is_a  phosphorylation of RNA polymerase II C-terminal domain
phosphorylation of RNA polymerase II C-terminal domain serine 5 residues (GO:0071620) [is_a relation] is_a  phosphorylation of RNA polymerase II C-terminal domain
positive regulation of phosphorylation of RNA polymerase II C-terminal domain (GO:1901409) [positively_regulates relation] positively_regulates  phosphorylation of RNA polymerase II C-terminal domain
regulation of phosphorylation of RNA polymerase II C-terminal domain (GO:1901407) [regulates relation] regulates  phosphorylation of RNA polymerase II C-terminal domain
None.