Term Information [More information on death domain binding]

Accession
GO:0070513
Name
death domain binding
Ontology
molecular_function
Synonyms
None
Definition
Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. Source: GOC:rl, InterPro:IPR000488, GOC:BHF, Pfam:PF00531
Comment
For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.
History
See term history for GO:0070513 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Contacting server...
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Graph of GO:0070513 from QuickGO

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Ancestors of death domain binding (GO:0070513)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
death domain binding [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
death domain binding [Inferred is_a relation] is_a (inferred) binding (GO:0005488)
death domain binding [Inferred is_a relation] is_a (inferred) protein binding (GO:0005515)
death domain binding [is_a relation] is_a  protein domain specific binding (GO:0019904)
Children of death domain binding (GO:0070513)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
BH3 domain binding (GO:0051434) [is_a relation] is_a  death domain binding
None.