Term Information [More information on ERK5 cascade]

Accession
GO:0070375
Name
ERK5 cascade
Ontology
biological_process
Synonyms
BMK cascade, BMK signaling pathway, BMK signalling pathway, BMK1 cascade, ERK5 signaling pathway, MAPK7 cascade, big MAP kinase signaling cascade, extracellular signal-regulated kinase 5 cascade
Definition
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. Source: ISBN:0896039986, PMID:20811974, GOC:signaling, GOC:add, PMID:16880823, PMID:16376520
Comment
None
History
See term history for GO:0070375 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0070375 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of ERK5 cascade (GO:0070375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ERK5 cascade [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
ERK5 cascade [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
ERK5 cascade [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
ERK5 cascade [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
ERK5 cascade [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
ERK5 cascade [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
ERK5 cascade [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
ERK5 cascade [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
ERK5 cascade [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
ERK5 cascade [Inferred occurs_in relation] occurs_in (inferred) cellular_component (GO:0005575)
ERK5 cascade [Inferred is_a relation] is_a (inferred) macromolecule modification (GO:0043412)
ERK5 cascade [Inferred is_a relation] is_a (inferred) phosphorus metabolic process (GO:0006793)
ERK5 cascade [Inferred is_a relation] is_a (inferred) protein metabolic process (GO:0019538)
ERK5 cascade [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
ERK5 cascade [Inferred occurs_in relation] occurs_in (inferred) cell (GO:0005623)
ERK5 cascade [Inferred is_a relation] is_a (inferred) cellular protein metabolic process (GO:0044267)
ERK5 cascade [Inferred is_a relation] is_a (inferred) phosphate-containing compound metabolic process (GO:0006796)
ERK5 cascade [Inferred is_a relation] is_a (inferred) protein modification process (GO:0036211)
ERK5 cascade [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
ERK5 cascade [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
ERK5 cascade [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
ERK5 cascade [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
ERK5 cascade [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
ERK5 cascade [Inferred occurs_in relation] occurs_in (inferred) cell part (GO:0044464)
ERK5 cascade [Inferred is_a relation] is_a (inferred) cellular protein modification process (GO:0006464)
ERK5 cascade [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
ERK5 cascade [Inferred is_a relation] is_a (inferred) phosphorylation (GO:0016310)
ERK5 cascade [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
ERK5 cascade [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
ERK5 cascade [Inferred occurs_in relation] occurs_in (inferred) intracellular (GO:0005622)
ERK5 cascade [Inferred is_a relation] is_a (inferred) protein phosphorylation (GO:0006468)
ERK5 cascade [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
ERK5 cascade [Inferred is_a relation] is_a (inferred) single-organism metabolic process (GO:0044710)
ERK5 cascade [Inferred is_a relation] is_a (inferred) intracellular signal transduction (GO:0035556)
ERK5 cascade [Inferred is_a relation] is_a (inferred) signal transduction by protein phosphorylation (GO:0023014)
ERK5 cascade [is_a relation] is_a  MAPK cascade (GO:0000165)
Children of ERK5 cascade (GO:0070375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of ERK5 cascade (GO:0070377) [negatively_regulates relation] negatively_regulates  ERK5 cascade
positive regulation of ERK5 cascade (GO:0070378) [positively_regulates relation] positively_regulates  ERK5 cascade
regulation of ERK5 cascade (GO:0070376) [regulates relation] regulates  ERK5 cascade
None.