Term Information [More information on necroptotic process]

Accession
GO:0070266
Name
necroptotic process
Ontology
biological_process
Synonyms
alt. id: GO:0060555, GO:0060554, GO:0060553
activation of necroptosis, activation of necroptosis by extracellular signals, activation of necroptosis in response to extracellular signals, activation of necroptosis of activated-T cells, establishment of necroptosis, establishment of necroptosis of activated-T cells, extracellular signal-induced necroptosis, TNF-induced necroptosis, necroptosis, induction of necroptosis, induction of necroptosis by extracellular signals, induction of necroptosis of activated-T cells, programmed necrotic cell death
Definition
A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former. Source: GOC:dph, PMID:20823910, GOC:tb, GOC:mtg_apoptosis, GOC:mah, PMID:18846107, PMID:21760595, PMID:21737330, PMID:21876153, GOC:BHF
Comment
Examples of this are Birc2 and Birc3 (UniProt symbols Q62210 and O08863) in PMID:21052097.
History
See term history for GO:0070266 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0070266 from QuickGO

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Ancestors of necroptotic process (GO:0070266)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
necroptotic process [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
necroptotic process [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
necroptotic process [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
necroptotic process [Inferred is_a relation] is_a (inferred) death (GO:0016265)
necroptotic process [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
necroptotic process [Inferred is_a relation] is_a (inferred) cell death (GO:0008219)
necroptotic process [Inferred is_a relation] is_a (inferred) necrotic cell death (GO:0070265)
necroptotic process [Inferred is_a relation] is_a (inferred) programmed cell death (GO:0012501)
necroptotic process [is_a relation] is_a  programmed necrotic cell death (GO:0097300)
Children of necroptotic process (GO:0070266)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
execution phase of necroptosis (GO:0097528) [part_of relation] part_of  necroptotic process
necroptotic signaling pathway (GO:0097527) [part_of relation] part_of  necroptotic process
negative regulation of necroptotic process (GO:0060546) [negatively_regulates relation] negatively_regulates  necroptotic process
positive regulation of necroptotic process (GO:0060545) [positively_regulates relation] positively_regulates  necroptotic process
regulation of necroptotic process (GO:0060544) [regulates relation] regulates  necroptotic process
ripoptosome assembly involved in necroptotic process (GO:1901026) [part_of relation] part_of  necroptotic process
None.