Term Information [More information on peroxiredoxin activity]

Accession
GO:0051920
Name
peroxiredoxin activity
Ontology
molecular_function
Synonyms
PRDX activity, Prx activity, thiol-containing-reductant:hydroperoxide oxidoreductase activity, AhpC activity, alkyl hydroperoxide reductase C22 activity
Definition
Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. Source: EC:1.11.1.15
Comment
Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.
History
See term history for GO:0051920 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0051920 from QuickGO

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Ancestors of peroxiredoxin activity (GO:0051920)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
peroxiredoxin activity [Inferred occurs_in relation] occurs_in (inferred) material anatomical entity (CARO:0000006)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
peroxiredoxin activity [Inferred occurs_in relation] occurs_in (inferred) anatomical structure (CARO:0000003)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) response to toxic substance (GO:0009636)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
peroxiredoxin activity [Inferred occurs_in relation] occurs_in (inferred) cell (CL:0000000)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) detoxification (GO:0098754)
peroxiredoxin activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
peroxiredoxin activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) cellular detoxification (GO:1990748)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
peroxiredoxin activity [Inferred part_of relation] part_of (inferred) cellular oxidant detoxification (GO:0098869)
peroxiredoxin activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
peroxiredoxin activity [is_a relation] is_a  antioxidant activity (GO:0016209)
peroxiredoxin activity [is_a relation] is_a  oxidoreductase activity, acting on peroxide as acceptor (GO:0016684)
Children of peroxiredoxin activity (GO:0051920)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
peroxynitrite reductase activity (GO:0072541) [is_a relation] is_a  peroxiredoxin activity
thioredoxin peroxidase activity (GO:0008379) [is_a relation] is_a  peroxiredoxin activity
tryparedoxin peroxidase activity (GO:0033196) [is_a relation] is_a  peroxiredoxin activity