Term Information [More information on G-quadruplex DNA binding]

Accession
GO:0051880
Name
G-quadruplex DNA binding
Ontology
molecular_function
Synonyms
G quadruplex DNA binding, G quartet DNA binding, G-DNA binding, G-quartet DNA binding, quadruplex DNA binding, tetraplex DNA binding, G quartet binding, G-quartet binding
Definition
Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. Source: PMID:9512530, PMID:16142245
Comment
None
History
See term history for GO:0051880 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0051880 from QuickGO

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Ancestors of G-quadruplex DNA binding (GO:0051880)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
G-quadruplex DNA binding [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
G-quadruplex DNA binding [Inferred is_a relation] is_a (inferred) binding (GO:0005488)
G-quadruplex DNA binding [Inferred is_a relation] is_a (inferred) heterocyclic compound binding (GO:1901363)
G-quadruplex DNA binding [Inferred is_a relation] is_a (inferred) organic cyclic compound binding (GO:0097159)
G-quadruplex DNA binding [Inferred is_a relation] is_a (inferred) nucleic acid binding (GO:0003676)
G-quadruplex DNA binding [Inferred is_a relation] is_a (inferred) DNA binding (GO:0003677)
G-quadruplex DNA binding [is_a relation] is_a  structure-specific DNA binding (GO:0043566)

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