Term Information [More information on methotrexate binding]

Accession
GO:0051870
Name
methotrexate binding
Ontology
molecular_function
Synonyms
None
Definition
Interacting selectively and non-covalently with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. Source: GOC:nln
Comment
None
History
See term history for GO:0051870 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Contacting server...
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Graph of GO:0051870 from QuickGO

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Ancestors of methotrexate binding (GO:0051870)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
methotrexate binding [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
methotrexate binding [is_a relation] is_a  binding (GO:0005488)
methotrexate binding [Inferred is_a relation] is_a (inferred) ion binding (GO:0043167)
methotrexate binding [Inferred is_a relation] is_a (inferred) small molecule binding (GO:0036094)
methotrexate binding [Inferred is_a relation] is_a (inferred) anion binding (GO:0043168)
methotrexate binding [Inferred is_a relation] is_a (inferred) organic acid binding (GO:0043177)
methotrexate binding [is_a relation] is_a  amide binding (GO:0033218)
methotrexate binding [is_a relation] is_a  carboxylic acid binding (GO:0031406)
methotrexate binding [is_a relation] is_a  drug binding (GO:0008144)
methotrexate binding [is_a relation] is_a  heterocyclic compound binding (GO:1901363)
methotrexate binding [is_a relation] is_a  organic cyclic compound binding (GO:0097159)

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None.