Term Information [More information on leukocyte tethering or rolling]

Accession
GO:0050901
Name
leukocyte tethering or rolling
Ontology
biological_process
Synonyms
None
Definition
Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). Source: PMID:7507411, Wikipedia:Leukocyte_extravasation, PMID:14680625, ISBN:0781735149, PMID:8600538, GOC:bf, PMID:14708592
Comment
None
History
See term history for GO:0050901 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0050901 from QuickGO

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Ancestors of leukocyte tethering or rolling (GO:0050901)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
leukocyte tethering or rolling [Inferred is_a relation] is_a (inferred) biological adhesion (GO:0022610)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) localization (GO:0051179)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
leukocyte tethering or rolling [Inferred is_a relation] is_a (inferred) cell adhesion (GO:0007155)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) localization of cell (GO:0051674)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) locomotion (GO:0040011)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) movement of cell or subcellular component (GO:0006928)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) cell motility (GO:0048870)
leukocyte tethering or rolling [Inferred is_a relation] is_a (inferred) cell-cell adhesion (GO:0098609)
leukocyte tethering or rolling [Inferred is_a relation] is_a (inferred) single organism cell adhesion (GO:0098602)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) cell migration (GO:0016477)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) immune system process (GO:0002376)
leukocyte tethering or rolling [Inferred is_a relation] is_a (inferred) single organismal cell-cell adhesion (GO:0016337)
leukocyte tethering or rolling [Inferred is_a relation] is_a (inferred) leukocyte cell-cell adhesion (GO:0007159)
leukocyte tethering or rolling [Inferred part_of relation] part_of (inferred) leukocyte migration (GO:0050900)
leukocyte tethering or rolling [part_of relation] part_of  cellular extravasation (GO:0045123)
leukocyte tethering or rolling [is_a relation] is_a  leukocyte adhesion to vascular endothelial cell (GO:0061756)
Children of leukocyte tethering or rolling (GO:0050901)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of leukocyte tethering or rolling (GO:1903237) [negatively_regulates relation] negatively_regulates  leukocyte tethering or rolling
positive regulation of leukocyte tethering or rolling (GO:1903238) [positively_regulates relation] positively_regulates  leukocyte tethering or rolling
regulation of leukocyte tethering or rolling (GO:1903236) [regulates relation] regulates  leukocyte tethering or rolling
None.