Term Information [More information on vascular endothelial growth factor receptor signaling pathway]

Accession
GO:0048010
Name
vascular endothelial growth factor receptor signaling pathway
Ontology
biological_process
Synonyms
VEGF receptor signaling pathway, VEGF receptor signalling pathway, VEGFR signaling pathway
Definition
Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. Source: PR:000001971, GOC:signaling, GOC:ceb
Comment
In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. In contrast, the VEGFR refers to PR:000001971. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0048010 is for annotation of any pathway in which a ligand (VEGF or an alternative growth factor) binds and activates a VEGFR (PR:000001971). For annotation of signaling pathways where a VEGF binds to a cell surface receptor (VEGFR, PDGFR etc.), consider 'vascular endothelial growth factor signaling pathway ; GO:0038084'.
History
See term history for GO:0048010 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0048010 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of vascular endothelial growth factor receptor signaling pathway (GO:0048010)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
vascular endothelial growth factor receptor signaling pathway [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
vascular endothelial growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
vascular endothelial growth factor receptor signaling pathway [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
vascular endothelial growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
vascular endothelial growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
vascular endothelial growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
vascular endothelial growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
vascular endothelial growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) cell surface receptor signaling pathway (GO:0007166)
vascular endothelial growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) enzyme linked receptor protein signaling pathway (GO:0007167)
vascular endothelial growth factor receptor signaling pathway [is_a relation] is_a  transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)
Children of vascular endothelial growth factor receptor signaling pathway (GO:0048010)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) [negatively_regulates relation] negatively_regulates  vascular endothelial growth factor receptor signaling pathway
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway (GO:0038033) [is_a relation] is_a  vascular endothelial growth factor receptor signaling pathway
positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) [positively_regulates relation] positively_regulates  vascular endothelial growth factor receptor signaling pathway
regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947) [regulates relation] regulates  vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment (GO:0060851) [is_a relation] is_a  vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor-1 signaling pathway (GO:0036323) [is_a relation] is_a  vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor-2 signaling pathway (GO:0036324) [is_a relation] is_a  vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor-3 signaling pathway (GO:0036325) [is_a relation] is_a  vascular endothelial growth factor receptor signaling pathway