Term Information [More information on bone remodeling]

Accession
GO:0046849
Name
bone remodeling
Ontology
biological_process
Synonyms
bone remodelling
Definition
The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. Source: GOC:curators
Comment
None
History
See term history for GO:0046849 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0046849 from QuickGO

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Ancestors of bone remodeling (GO:0046849)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
bone remodeling [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
bone remodeling [Inferred is_a relation] is_a (inferred) multicellular organismal process (GO:0032501)
bone remodeling [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
bone remodeling [Inferred is_a relation] is_a (inferred) single-multicellular organism process (GO:0044707)
bone remodeling [is_a relation] is_a  tissue remodeling (GO:0048771)
Children of bone remodeling (GO:0046849)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
bone resorption (GO:0045453) [part_of relation] part_of  bone remodeling
negative regulation of bone remodeling (GO:0046851) [negatively_regulates relation] negatively_regulates  bone remodeling
ossification involved in bone remodeling (GO:0043932) [part_of relation] part_of  bone remodeling
positive regulation of bone remodeling (GO:0046852) [positively_regulates relation] positively_regulates  bone remodeling
regulation of bone remodeling (GO:0046850) [regulates relation] regulates  bone remodeling
Wikipedia
Bone_remodeling