Term Information [More information on pyruvate dehydrogenase complex]

Accession
GO:0045254
Name
pyruvate dehydrogenase complex
Ontology
cellular_component
Synonyms
alt. id: GO:0009364
pyruvate dehydrogenase complex (lipoamide), dihydrolipoyl dehydrogenase complex
Definition
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Source: ISBN:0716720094
Comment
Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.
History
See term history for GO:0045254 at QuickGO
Subset
gosubset_prok
goslim_pir
Community
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Feedback
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Graph of GO:0045254 from QuickGO

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Ancestors of pyruvate dehydrogenase complex (GO:0045254)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism process (GO:0044699)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism metabolic process (GO:0044710)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) biosynthetic process (GO:0009058)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism cellular process (GO:0044763)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) small molecule metabolic process (GO:0044281)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular biosynthetic process (GO:0044249)
pyruvate dehydrogenase complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) cofactor metabolic process (GO:0051186)
pyruvate dehydrogenase complex [Inferred capable_of relation] capable_of (inferred) molecular_function (GO:0003674)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic acid metabolic process (GO:0006082)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) sulfur compound metabolic process (GO:0006790)
pyruvate dehydrogenase complex [Inferred capable_of relation] capable_of (inferred) catalytic activity (GO:0003824)
pyruvate dehydrogenase complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) coenzyme metabolic process (GO:0006732)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) cofactor biosynthetic process (GO:0051188)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance biosynthetic process (GO:1901576)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) oxidation-reduction process (GO:0055114)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) oxoacid metabolic process (GO:0043436)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) phosphorus metabolic process (GO:0006793)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) sulfur compound biosynthetic process (GO:0044272)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) thioester metabolic process (GO:0035383)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) acyl-CoA metabolic process (GO:0006637)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) carboxylic acid metabolic process (GO:0019752)
pyruvate dehydrogenase complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) coenzyme biosynthetic process (GO:0009108)
pyruvate dehydrogenase complex [Inferred capable_of relation] capable_of (inferred) oxidoreductase activity (GO:0016491)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) thioester biosynthetic process (GO:0035384)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) acetyl-CoA metabolic process (GO:0006084)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) acyl-CoA biosynthetic process (GO:0071616)
pyruvate dehydrogenase complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
pyruvate dehydrogenase complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) monocarboxylic acid metabolic process (GO:0032787)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) oxidoreductase activity, acting on the aldehyde or oxo group of donors (GO:0016903)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) acetyl-CoA biosynthetic process (GO:0006085)
pyruvate dehydrogenase complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
pyruvate dehydrogenase complex [Inferred capable_of relation] capable_of (inferred) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620)
pyruvate dehydrogenase complex [is_a relation] is_a  protein complex (GO:0043234)
pyruvate dehydrogenase complex [Inferred capable_of relation] capable_of (inferred) pyruvate dehydrogenase activity (GO:0004738)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) pyruvate metabolic process (GO:0006090)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism biosynthetic process (GO:0044711)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) acetyl-CoA biosynthetic process from pyruvate (GO:0006086)
pyruvate dehydrogenase complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
pyruvate dehydrogenase complex [Inferred part_of relation] part_of (inferred) cytoplasm (GO:0005737)
pyruvate dehydrogenase complex [Inferred capable_of part of relation] capable_of part of (inferred) pyruvate dehydrogenase [NAD(P)+] activity (GO:0034603)
pyruvate dehydrogenase complex [is_a relation] is_a  cytoplasmic part (GO:0044444)
pyruvate dehydrogenase complex [is_a relation] is_a  oxidoreductase complex (GO:1990204)
pyruvate dehydrogenase complex [capable_of relation] capable_of  pyruvate dehydrogenase (NAD+) activity (GO:0034604)
Children of pyruvate dehydrogenase complex (GO:0045254)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytosolic pyruvate dehydrogenase complex (GO:0045250) [is_a relation] is_a  pyruvate dehydrogenase complex
mitochondrial pyruvate dehydrogenase complex (GO:0005967) [is_a relation] is_a  pyruvate dehydrogenase complex
plastid pyruvate dehydrogenase complex (GO:0010240) [is_a relation] is_a  pyruvate dehydrogenase complex