Term Information [More information on T-helper 1 cell differentiation]

Accession
GO:0045063
Name
T-helper 1 cell differentiation
Ontology
biological_process
Synonyms
T-helper 1 cell development
Definition
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. Source: CL:0000545, GOC:ebc
Comment
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0045063 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0045063 from QuickGO

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Ancestors of T-helper 1 cell differentiation (GO:0045063)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) biological adhesion (GO:0022610)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) developmental process (GO:0032502)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) multicellular organismal process (GO:0032501)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) anatomical structure development (GO:0048856)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) cell adhesion (GO:0007155)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) single-multicellular organism process (GO:0044707)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) single-organism developmental process (GO:0044767)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) cell-cell adhesion (GO:0098609)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) multicellular organism development (GO:0007275)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) single organism cell adhesion (GO:0098602)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) immune system process (GO:0002376)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) single organismal cell-cell adhesion (GO:0016337)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) system development (GO:0048731)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) animal organ development (GO:0048513)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) immune system development (GO:0002520)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) leukocyte cell-cell adhesion (GO:0007159)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) cell activation (GO:0001775)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) cellular developmental process (GO:0048869)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) hematopoietic or lymphoid organ development (GO:0048534)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) immune effector process (GO:0002252)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) immune response (GO:0006955)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) leukocyte aggregation (GO:0070486)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) cell activation involved in immune response (GO:0002263)
T-helper 1 cell differentiation [is_a relation] is_a  cell differentiation (GO:0030154)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) hemopoiesis (GO:0030097)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) leukocyte activation (GO:0045321)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) lymphocyte aggregation (GO:0071593)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) leukocyte activation involved in immune response (GO:0002366)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) leukocyte differentiation (GO:0002521)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) lymphocyte activation (GO:0046649)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) T cell aggregation (GO:0070489)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) lymphocyte activation involved in immune response (GO:0002285)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) lymphocyte differentiation (GO:0030098)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) T cell activation (GO:0042110)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) alpha-beta T cell activation (GO:0046631)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) T cell activation involved in immune response (GO:0002286)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) T cell differentiation (GO:0030217)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) alpha-beta T cell activation involved in immune response (GO:0002287)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) alpha-beta T cell differentiation (GO:0046632)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) CD4-positive, alpha-beta T cell activation (GO:0035710)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) T cell differentiation involved in immune response (GO:0002292)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) adaptive immune response (GO:0002250)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) alpha-beta T cell differentiation involved in immune response (GO:0002293)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) CD4-positive, alpha-beta T cell differentiation (GO:0043367)
T-helper 1 cell differentiation [Inferred part_of relation] part_of (inferred) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460)
T-helper 1 cell differentiation [Inferred is_a relation] is_a (inferred) CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)
T-helper 1 cell differentiation [part_of relation] part_of  T-helper 1 type immune response (GO:0042088)
T-helper 1 cell differentiation [is_a relation] is_a  T-helper cell differentiation (GO:0042093)
Children of T-helper 1 cell differentiation (GO:0045063)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of T-helper 1 cell differentiation (GO:0045626) [negatively_regulates relation] negatively_regulates  T-helper 1 cell differentiation
positive regulation of T-helper 1 cell differentiation (GO:0045627) [positively_regulates relation] positively_regulates  T-helper 1 cell differentiation
regulation of T-helper 1 cell differentiation (GO:0045625) [regulates relation] regulates  T-helper 1 cell differentiation
T-helper 1 cell lineage commitment (GO:0002296) [part_of relation] part_of  T-helper 1 cell differentiation
None.