Term Information [More information on cell dedifferentiation]

Accession
GO:0043697
Name
cell dedifferentiation
Ontology
biological_process
Synonyms
None
Definition
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. Source: GOC:dph, GOC:pg
Comment
Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer.
History
See term history for GO:0043697 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0043697 from QuickGO

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Ancestors of cell dedifferentiation (GO:0043697)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cell dedifferentiation [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
cell dedifferentiation [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
cell dedifferentiation [Inferred is_a relation] is_a (inferred) developmental process (GO:0032502)
cell dedifferentiation [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
cell dedifferentiation [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
cell dedifferentiation [Inferred is_a relation] is_a (inferred) single-organism developmental process (GO:0044767)
cell dedifferentiation [is_a relation] is_a  cellular developmental process (GO:0048869)
cell dedifferentiation [is_a relation] is_a  dedifferentiation (GO:0043696)
Children of cell dedifferentiation (GO:0043697)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cell dedifferentiation involved in phenotypic switching (GO:0090678) [is_a relation] is_a  cell dedifferentiation
hepatocyte dedifferentiation (GO:1990828) [is_a relation] is_a  cell dedifferentiation
None.