Term Information [More information on post-translational protein modification]

Accession
GO:0043687
Name
post-translational protein modification
Ontology
biological_process
Synonyms
PTM, post-translational amino acid modification, post-translational modification, posttranslational amino acid modification, posttranslational modification, posttranslational protein modification
Definition
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. Source: GOC:jsg
Comment
This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
History
See term history for GO:0043687 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0043687 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of post-translational protein modification (GO:0043687)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
post-translational protein modification [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
post-translational protein modification [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
post-translational protein modification [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
post-translational protein modification [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
post-translational protein modification [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
post-translational protein modification [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
post-translational protein modification [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
post-translational protein modification [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
post-translational protein modification [Inferred is_a relation] is_a (inferred) macromolecule modification (GO:0043412)
post-translational protein modification [Inferred is_a relation] is_a (inferred) protein metabolic process (GO:0019538)
post-translational protein modification [Inferred is_a relation] is_a (inferred) cellular protein metabolic process (GO:0044267)
post-translational protein modification [Inferred is_a relation] is_a (inferred) protein modification process (GO:0036211)
post-translational protein modification [is_a relation] is_a  cellular protein modification process (GO:0006464)
Children of post-translational protein modification (GO:0043687)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
C-terminal protein amino acid modification (GO:0018410) [is_a relation] is_a  post-translational protein modification
CAAX-box protein modification (GO:0071587) [is_a relation] is_a  post-translational protein modification
N-terminal protein amino acid propionylation (GO:0061606) [is_a relation] is_a  post-translational protein modification
negative regulation of post-translational protein modification (GO:1901874) [negatively_regulates relation] negatively_regulates  post-translational protein modification
positive regulation of post-translational protein modification (GO:1901875) [positively_regulates relation] positively_regulates  post-translational protein modification
post-translational protein acetylation (GO:0034421) [is_a relation] is_a  post-translational protein modification
regulation of post-translational protein modification (GO:1901873) [regulates relation] regulates  post-translational protein modification