Term Information [More information on 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex]

Accession
GO:0043540
Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
Ontology
cellular_component
Synonyms
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex
Definition
A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis. Source: GOC:so, GOC:jl
Comment
Note that we use this single class to represent all 4 isoforms of this complex. We decided to do this because the isoforms do not differ in function, rather in expression and regulation. We may want to revisit this in future.
History
See term history for GO:0043540 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0043540 from QuickGO

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Ancestors of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex (GO:0043540)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nitrogen compound metabolic process (GO:0006807)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism process (GO:0044699)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular aromatic compound metabolic process (GO:0006725)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular nitrogen compound metabolic process (GO:0034641)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) heterocycle metabolic process (GO:0046483)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic cyclic compound metabolic process (GO:1901360)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) primary metabolic process (GO:0044238)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism metabolic process (GO:0044710)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleobase-containing compound metabolic process (GO:0006139)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) phosphorus metabolic process (GO:0006793)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism cellular process (GO:0044763)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) small molecule metabolic process (GO:0044281)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) carbohydrate derivative metabolic process (GO:1901135)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleobase-containing small molecule metabolic process (GO:0055086)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organophosphate metabolic process (GO:0019637)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) phosphate-containing compound metabolic process (GO:0006796)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glycosyl compound metabolic process (GO:1901657)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleoside phosphate metabolic process (GO:0006753)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organonitrogen compound metabolic process (GO:1901564)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) catabolic process (GO:0009056)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) cofactor metabolic process (GO:0051186)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleoside diphosphate metabolic process (GO:0009132)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleoside metabolic process (GO:0009116)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleoside monophosphate metabolic process (GO:0009123)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleoside triphosphate metabolic process (GO:0009141)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleotide metabolic process (GO:0009117)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic acid metabolic process (GO:0006082)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine-containing compound metabolic process (GO:0072521)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ribose phosphate metabolic process (GO:0019693)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) carbohydrate metabolic process (GO:0005975)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) coenzyme metabolic process (GO:0006732)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of relation] capable_of (inferred) molecular_function (GO:0003674)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance catabolic process (GO:1901575)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) oxoacid metabolic process (GO:0043436)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) phosphorylation (GO:0016310)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine nucleoside diphosphate metabolic process (GO:0009135)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine nucleoside metabolic process (GO:0042278)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine nucleoside monophosphate metabolic process (GO:0009126)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine nucleoside triphosphate metabolic process (GO:0009144)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine nucleotide metabolic process (GO:0006163)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ribonucleoside diphosphate metabolic process (GO:0009185)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ribonucleoside metabolic process (GO:0009119)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ribonucleoside monophosphate metabolic process (GO:0009161)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ribonucleoside triphosphate metabolic process (GO:0009199)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ribonucleotide metabolic process (GO:0009259)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) carbohydrate catabolic process (GO:0016052)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) carboxylic acid metabolic process (GO:0019752)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) catalytic activity (GO:0003824)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleotide phosphorylation (GO:0046939)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) oxidoreduction coenzyme metabolic process (GO:0006733)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine ribonucleoside diphosphate metabolic process (GO:0009179)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine ribonucleoside metabolic process (GO:0046128)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine ribonucleoside monophosphate metabolic process (GO:0009167)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine ribonucleoside triphosphate metabolic process (GO:0009205)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) purine ribonucleotide metabolic process (GO:0009150)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) pyridine-containing compound metabolic process (GO:0072524)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism carbohydrate metabolic process (GO:0044723)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism catabolic process (GO:0044712)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ADP metabolic process (GO:0046031)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ATP metabolic process (GO:0046034)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) biosynthetic process (GO:0009058)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) generation of precursor metabolites and energy (GO:0006091)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) monocarboxylic acid metabolic process (GO:0032787)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) monosaccharide metabolic process (GO:0005996)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleoside diphosphate phosphorylation (GO:0006165)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) pyridine nucleotide metabolic process (GO:0019362)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism carbohydrate catabolic process (GO:0044724)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) small molecule catabolic process (GO:0044282)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of relation] capable_of (inferred) transferase activity (GO:0016740)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) ATP generation from ADP (GO:0006757)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular carbohydrate metabolic process (GO:0044262)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) hexose metabolic process (GO:0019318)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) monosaccharide catabolic process (GO:0046365)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) nicotinamide nucleotide metabolic process (GO:0046496)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance biosynthetic process (GO:1901576)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) pyruvate metabolic process (GO:0006090)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism biosynthetic process (GO:0044711)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of relation] capable_of (inferred) transferase activity, transferring phosphorus-containing groups (GO:0016772)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) carbohydrate biosynthetic process (GO:0016051)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) carbohydrate phosphorylation (GO:0046835)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) cytoplasm (GO:0005737)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glucose metabolic process (GO:0006006)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glycolytic process (GO:0006096)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) hexose catabolic process (GO:0019320)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) kinase activity (GO:0016301)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) NAD metabolic process (GO:0019674)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [is_a relation] is_a  protein complex (GO:0043234)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) small molecule biosynthetic process (GO:0044283)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of relation] capable_of (inferred) carbohydrate kinase activity (GO:0019200)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) cytoplasmic part (GO:0044444)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glucose catabolic process (GO:0006007)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glycolytic process through fructose-6-phosphate (GO:0061615)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) monosaccharide biosynthetic process (GO:0046364)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) NADH metabolic process (GO:0006734)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) oxidation-reduction process (GO:0055114)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of relation] capable_of (inferred) phosphotransferase activity, alcohol group as acceptor (GO:0016773)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred part_of relation] part_of (inferred) cytosol (GO:0005829)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glucose catabolic process to pyruvate (GO:0061718)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) glycolytic process through glucose-6-phosphate (GO:0061620)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) hexose biosynthetic process (GO:0019319)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) NADH regeneration (GO:0006735)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of relation] capable_of (inferred) phosphofructokinase activity (GO:0008443)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [is_a relation] is_a  transferase complex (GO:1990234)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [Inferred capable_of part of relation] capable_of part of (inferred) 6-phosphofructo-2-kinase activity (GO:0003873)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [capable_of part of relation] capable_of part of  canonical glycolysis (GO:0061621)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [is_a relation] is_a  cytosolic part (GO:0044445)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [capable_of part of relation] capable_of part of  gluconeogenesis (GO:0006094)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [is_a relation] is_a  transferase complex, transferring phosphorus-containing groups (GO:0061695)

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