Term Information [More information on malate-aspartate shuttle]

Accession
GO:0043490
Name
malate-aspartate shuttle
Ontology
biological_process
Synonyms
malate aspartate shuttle, malate/aspartate shuttle, malate:aspartate shuttle
Definition
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle. Source: ISBN:0716743663, GOC:mtg_electron_transport, GOC:jl
Comment
None
History
See term history for GO:0043490 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0043490 from QuickGO

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Ancestors of malate-aspartate shuttle (GO:0043490)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
malate-aspartate shuttle [Inferred occurs_in relation] occurs_in (inferred) cellular_component (GO:0005575)
malate-aspartate shuttle [Inferred occurs_in relation] occurs_in (inferred) cell (GO:0005623)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) localization (GO:0051179)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
malate-aspartate shuttle [Inferred occurs_in relation] occurs_in (inferred) cell part (GO:0044464)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) cellular localization (GO:0051641)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) establishment of localization (GO:0051234)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) establishment of localization in cell (GO:0051649)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) generation of precursor metabolites and energy (GO:0006091)
malate-aspartate shuttle [Inferred occurs_in relation] occurs_in (inferred) intracellular (GO:0005622)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) single-organism localization (GO:1902578)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) transport (GO:0006810)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) energy derivation by oxidation of organic compounds (GO:0015980)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) intracellular transport (GO:0046907)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) single-organism transport (GO:0044765)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) cellular respiration (GO:0045333)
malate-aspartate shuttle [Inferred part_of relation] part_of (inferred) electron transport chain (GO:0022900)
malate-aspartate shuttle [Inferred is_a relation] is_a (inferred) single-organism intracellular transport (GO:1902582)
malate-aspartate shuttle [is_a relation] is_a  mitochondrial transport (GO:0006839)
malate-aspartate shuttle [part_of relation] part_of  respiratory electron transport chain (GO:0022904)

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